Musculosketal infections are potentially devastating for the patient his family and the health care services as they may lead to functional impairment long lasting disability or even permanent handicap. This problem may also have socioeconomic implications. Infection commonly results in prolonged use of antibiotics multiple operations complications extended rehabilitation and long lasting followup visits with additional costs for the health care provider. This book covers contributions from international experts who came together in Potsdam Germany at the invitation of Professor Heino Kienapfel MD PhD of the Department of Special Orthopaedic Surgery and Traumatology of the Centre of Joint Arthroplasty Auguste Viktoria Clinics Berlin. The focus of this book is the state of the art of: -Antimicrobial Resistances: Facts and Statistics - Arthroplasty Registers in EU: Status and Development - Microbiology in Arthroplasty - Strategies in Antibiotic Treatment - Spacer Management: Clinical Experiences and Requirements - Biofilm Creation: Low Grade Infection - Revision: Cemented vs. Cementless - Revision: One-stage vs. Two-stage treatment