16 Hour Pain Relief from Lower Back Pains & Hip Pains Unlike other creams rubs and patches which create sensations on your skin to mask pain ThermaCare Heatwraps use real heat therapy to accelerate healing and relieve pain at the source for up to 8 hours and once removed another 8 hours?that?s 16 hours of relief from aches and pains. How To Use: 1. Ensure skin in application area is clean dry and free of makeup recently applied skin moisturizer lotions and other topical analgesics. 2. Position wrap flat on your skin and ensure the darker heat cells are placed towards skin. 3. Use care when handling the wrap to prevent over-tightening.(1) (1) Read full product labeling for complete usage instructions.