Compare to the active ingredient of Tylenol 8HR Arthritis Pain. Don't let arthritis pain keep you from doing what you love. Equate Acetaminophen Extended-Release Tablets, 650 mg is a pain reliever/fever reducer that provides temporary relief of minor arthritis pain for up to 8 hours. It also helps to temporarily reduce fever and relieve minor aches and pains due to the common cold, premenstrual and menstrual cramps, headache, backache, toothache and other muscular aches. Effective for minor arthritis pain. Contains 650 mg of acetaminophen in each extended-release tablet. For adults 18 years and older. This product is free of aspirin and gluten.